An Atoh1 CRE Knock-In Mouse Labels Motor Neurons Involved in Fine Motor Control
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چکیده
منابع مشابه
eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model.
Understanding mechanisms that lead to selective motor neuron degeneration requires visualization and cellular identification of vulnerable neurons. Here we report generation and characterization of UCHL1-eGFP and hSOD1(G93A)-UeGFP mice, novel reporter lines for cortical and spinal motor neurons. Corticospinal motor neurons (CSMN) and a subset of spinal motor neurons (SMN) are genetically labele...
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ژورنال
عنوان ژورنال: eneuro
سال: 2021
ISSN: 2373-2822
DOI: 10.1523/eneuro.0221-20.2021